MSC and HUVEC co-cultured fillers overcome intractable fistula in a new mouse model.

Anastomotic leakage can lead to intractable fistulae after gastrointestinal surgery in patients with severe comorbidities. In this study, we aimed to devise new intractable fistula mouse models and evaluate the utility of the fillers containing human mesenchymal stem cells (MSCs) and human umbilical...

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Bibliographic Details
Main Authors: Soichiro Hirasawa, Kentaro Murakami, Masayuki Kano, Satoshi Endo, Takeshi Toyozumi, Yasunori Matsumoto, Ryota Otsuka, Nobufumi Sekino, Tadashi Shiraishi, Takahiro Ryuzaki, Kazuya Kinoshita, Takuma Sasaki, Hisahiro Matsubara
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0330478
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