Chicken GSDME, a major pore-forming molecule responsible for RNA virus-induced pyroptosis in chicken
ABSTRACT Pyroptosis is an inflammatory type of programmed cell death that mainly depends on the formation of plasma membrane pores by Gasdermin D (GSDMD) in mammals. However, the genetic deficiency of GSDMD in chicken renders avian pyroptosis elusive. Here, we show that infection of DF-1 cells (a ch...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2025-01-01
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| Series: | Journal of Virology |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/jvi.01588-24 |
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