Cell culture NAIL-MS allows insight into human tRNA and rRNA modification dynamics in vivo
Post transcriptional modification of RNAs represents an important layer of gene regulation. Here the authors describe NAIL-MS—a method for monoisotopic RNA labeling in cell culture—demonstrating its capabilities by analyzing the modification kinetics of total tRNA, 18S rRNA and tRNAPhe as models.
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2021-01-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-020-20576-4 |
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