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Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Abstract Chimeric antigen receptor‐engineered natural killer T (CAR‐NKT) cell therapy represents a promising and innovative strategy in cancer immunotherapy, but is limited by acute toxicity and adverse effects, restricting broader clinical application despite durable responses. In this study, a nov...

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Hlavní autoři: Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2026-03-01
Edice:Advanced Science
Témata:
cancer therapy
CAR‐NKT
extracellular vesicles
immunotherapy
TM4SF1 nanobody
On-line přístup:https://doi.org/10.1002/advs.202521623
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