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Intrinsically disordered regions in TRPV2 mediate protein-protein interactions

Abstract Transient receptor potential (TRP) ion channels are gated by diverse intra- and extracellular stimuli leading to cation inflow (Na+, Ca2+) regulating many cellular processes and initiating organismic somatosensation. Structures of most TRP channels have been solved. However, structural and...

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Hlavní autoři: Raghavendar R. Sanganna Gari, Grigory Tagiltsev, Ruth A. Pumroy, Yining Jiang, Martin Blackledge, Vera Y. Moiseenkova-Bell, Simon Scheuring
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2023-09-01
Edice:Communications Biology
On-line přístup:https://doi.org/10.1038/s42003-023-05343-7
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