The Effect of Enantiomer Elution Order on the Determination of Minor Enantiomeric Impurity in Ketoprofen and Enantiomeric Purity Evaluation of Commercially Available Dexketoprofen Formulations

In a recent study, opposite enantiomer elution order was observed for ketoprofen enantiomers on two amylose-phenylcarbamate-based chiral columns with the same chemical composition of the chiral selector but in one case with coated while in the other with an immobilized chiral selector. In the presen...

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Auteurs principaux:	Kenan Can Tok, Mehmet Gumustas, Giorgi Jibuti, Halit Sinan Suzen, Sibel A. Ozkan, Bezhan Chankvetadze
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2020-12-01
Collection:	Molecules
Sujets:	enantiomeric impurity determination amylose tris(3-chloro-5-methylphenylcarbamate) enantiomer elution order reversal method validation dexketoprofen
Accès en ligne:	https://www.mdpi.com/1420-3049/25/24/5865
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