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PDCD4 as a marker of mTOR pathway activation and therapeutic target in mycobacterial infections

ABSTRACT Programmed cell death protein 4 (PDCD4) is instrumental in regulating a range of cellular processes such as translation, apoptosis, signal transduction, and inflammatory responses. There is a notable inverse correlation between PDCD4 and the mammalian target of rapamycin (mTOR) pathway, whi...

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Bibliografische Detailangaben
Hauptverfasser: Ruchi Paroha, Jia Wang, Sunhee Lee
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2024-08-01
Schriftenreihe:Microbiology Spectrum
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Online-Zugang:https://journals.asm.org/doi/10.1128/spectrum.00062-24
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