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Pseudolaric acid B induces G2/M phase arrest in canine mammary tumor cells by targeting CDK1

IntroductionCurrent management of canine mammary tumors (CMTs) remains reliant on surgical resection and chemotherapy. However, these strategies are often limited by high recurrence rates and systemic toxicity. Addressing these limitations requires urgent development of safer and more effective ther...

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Autori principali: Mengjuan Chen, Hui Han, Mengke Qin, Huixin Li, Qiqi Lu, Xin Huang, Qingda Meng, Shanshan Xie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-10-01
Serie:Frontiers in Veterinary Science
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Accesso online:https://www.frontiersin.org/articles/10.3389/fvets.2025.1644200/full
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