FAM3C/ILEI protein is elevated in psoriatic lesions and triggers psoriasiform hyperproliferation in mice

Abstract FAM3C/ILEI is an important cytokine for tumor progression and metastasis. However, its involvement in inflammation remains elusive. Here, we show that ILEI protein is highly expressed in psoriatic lesions. Inducible keratinocyte‐specific ILEI overexpression in mice (K5‐ILEIind) recapitulate...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Barizah Malik, Iva Vokic, Thomas Mohr, Marle Poppelaars, Martin Holcmann, Philipp Novoszel, Gerald Timelthaler, Thomas Lendl, Dana Krauss, Ulrich Elling, Michael Mildner, Josef M Penninger, Peter Petzelbauer, Maria Sibilia, Agnes Csiszar
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer Nature 2023-05-01
Sarja:	EMBO Molecular Medicine
Aiheet:	ILEI/FAM3C inflammation keratinocyte differentiation psoriasis uPA/PLAU
Linkit:	https://doi.org/10.15252/emmm.202216758
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