Exploring glucagon-like peptide-1 receptor agonists as potential disease-modifying agent in psychiatric and neurodevelopmental conditions: evidence from a drug target Mendelian randomization

Abstract Background Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have recently received Food and Drug Administration (FDA) approval for obesity management. However, the causal relationship between GLP-1RAs and psychiatric and neurodevelopmental conditions remains unclear. Methods We used Men...

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Autors principals:	Lingfeng Zhang, Xiang Chen, Yantao Xu, Jiachen Liu, Zhongchun Liu
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-05-01
Col·lecció:	BMC Psychiatry
Matèries:	GLP-1R agonists Psychiatric and neurodevelopmental conditions Drug target Mendelian randomization
Accés en línia:	https://doi.org/10.1186/s12888-025-06914-0
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