Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors

A series of sulfanilamide-1,2,3-triazole hybrids were designed by a molecular hybridization strategy and evaluated for antiproliferative activity against three selected cancer cell lines (MGC-803, MCF-7 and PC-3). The detailed structure-activity relationships for these sulfanilamide-1,2,3-triazole h...

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Principais autores:	Dong-Jun Fu, Ji-Feng Liu, Ruo-Han Zhao, Jia-Huan Li, Sai-Yang Zhang, Yan-Bing Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-09-01
Colecção:	Molecules
Assuntos:	sulfanilamide-1,2,3-triazole molecular hybridization strategy antiproliferative activity structure-activity relationships tubulin polymerization
Acesso em linha:	https://www.mdpi.com/1420-3049/22/9/1470
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