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Fontan associated protein-losing enteropathy is linked to distinct metabolic and hepatic alterations

Abstract The univentricular Fontan circulation is associated with long-term multiorgan complications, including protein-losing enteropathy (PLE). While hemodynamic and lymphatic contributors to PLE have been described, its systemic metabolic signature remains incompletely characterized. We aimed to...

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Principais autores: Christian Schroeder, Fabian B. Fahlbusch, Robert Cesnjevar, Manfred Rauh, Sven Dittrich, Julia Moosmann
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2026-02-01
סדרה:Scientific Reports
נושאים:
Fontan circulation
Protein-losing enteropathy (PLE)
Targeted metabolomics
Dyslipidemia
Phosphatidylcholine
Cholesterol
גישה מקוונת:https://doi.org/10.1038/s41598-026-37974-1
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