Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals

Abstract Background Both Alzheimer’s disease (AD) genetic risk factors and indices of cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether they interact. This study examined whether a CR index score modifies the relationship between AD genetic risk factors and l...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Corinne Pettigrew, Jurijs Nazarovs, Anja Soldan, Vikas Singh, Jiangxia Wang, Timothy Hohman, Logan Dumitrescu, Julia Libby, Brian Kunkle, Alden L. Gross, Sterling Johnson, Qiongshi Lu, Corinne Engelman, Colin L. Masters, Paul Maruff, Simon M. Laws, John C. Morris, Jason Hassenstab, Carlos Cruchaga, Susan M. Resnick, Melissa H. Kitner-Triolo, Yang An, Marilyn Albert
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2023-03-01
سلاسل:	Alzheimer’s Research & Therapy
الموضوعات:	Alzheimer’s disease Cognitive reserve Genetics Polygenic risk score APOE genotype Cognition
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13195-023-01206-9
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!