CD10+ neutrophils promote CD8+ T-cell depletion in mucosal malignant melanoma through the SELPG-SELL pathway

Objective·To compare the immune microenvironment of mucosal malignant melanoma (MM) and cutaneous malignant melanoma (CM) using single-cell transcriptome analysis system, and to elucidate the key regulatory mechanism of CD8+ T cell depletion in MM.Methods·A total of 36 531 cells from three treatment...

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Detalhes bibliográficos

Principais autores:	HAO Meiling, MA Yanni, MA Xuhui, ZHANG Yanjie, ZENG Hanlin, CHEN Shanshuang
Formato:	Artigo
Idioma:	Chinês
Publicado em:	Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2025-11-01
Colecção:	Shanghai Jiaotong Daxue xuebao. Yixue ban
Assuntos:	mucosal malignant melanoma neutrophils cd8+depleted t cells single-cell transcriptome
Acesso em linha:	https://xuebao.shsmu.edu.cn/article/2025/1674-8115/1674-8115-2025-45-11-1466.shtml
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