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Spatial multi-omics mapping of tumor microanatomy dynamics following radiotherapy combined with targeted-immunotherapy in hepatocellular carcinoma

Abstract Remodeling of the tumor microenvironment (TME) under therapeutic pressure is a critical determinant of treatment response and resistance in hepatocellular carcinoma (HCC). Triple-combination therapy integrating targeted agents, immune checkpoint inhibitors, and radiotherapy (T+I+R) has show...

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Bibliografiske detaljer
Principais autores: Fansen Ji, Haoming Xia, Ying Xiao, Jiawei Zhang, Hao Chen, Bingjun Tang, Huan Li, Hao Liu, Boyang Wu, Xiaojuan Wang, Shizhong Yang, Jiahong Dong
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-01-01
Serier:Biomarker Research
Online adgang:https://doi.org/10.1186/s40364-025-00876-x
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