Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
CRISPR/Cas9-based homing gene drives have emerged as a potential new approach to mosquito control. Here the authors use transgenic lines with germline-specific regulatory elements to express Cas9 and achieve up to 94% inheritance bias, closing the gap between A. aegyptidrives and the highly efficien...
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| Principais autores: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2023-01-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-023-36029-7 |
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