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Use of <it>nfsB</it>, encoding nitroreductase, as a reporter gene to determine the mutational spectrum of spontaneous mutations in <it>Neisseria gonorrhoeae</it>

<p>Abstract</p> <p>Background</p> <p>Organisms that are sensitive to nitrofurantoin express a nitroreductase. Since bacterial resistance to this compound results primarily from mutations in the gene encoding nitroreductase, the resulting loss of function of nitroreductase results in a selectable phe...

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Váldodahkkit: Dunham Stephen, Carrizosa Esteban, Stein Daniel C
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2009-11-01
Ráidu:BMC Microbiology
Liŋkkat:http://www.biomedcentral.com/1471-2180/9/239
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