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Essential Role of Histidine for Rapid Copper(II)-Mediated Disassembly of Neurokinin B Amyloid

Neurokinin B is a tachykinin peptide involved in a diverse range of neuronal functions. It rapidly forms an amyloid, which is considered physiologically important for efficient packing into dense core secretory vesicles within hypothalamic neurons. Disassembly of the amyloid is thought to require th...

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Autori principali: Bhawantha M. Jayawardena, Lorraine Peacey, Roland Gamsjaeger, Christopher E. Jones
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-10-01
Serie:Biomolecules
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Accesso online:https://www.mdpi.com/2218-273X/12/11/1585
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