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Stimulation of Metabotropic Glutamate (mGlu) 2 Receptor and Blockade of mGlu1 Receptor Improve Social Memory Impairment Elicited by MK-801 in Rats

Abstract.: Glutamatergic dysfunction has been implicated in psychiatric disorders such as schizophrenia. Both the stimulation of the metabotropic glutamate (mGlu) 2/3 receptor and the blockade of the mGlu1 receptor have been shown to be effective in a number of animal models of schizophrenia. Howeve...

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Bibliographische Detailangaben
Hauptverfasser: Hirohiko Hikichi, Ayaka Kaku, Jun-ichi Karasawa, Shigeyuki Chaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2013-01-01
Schriftenreihe:Journal of Pharmacological Sciences
Online Zugang:http://www.sciencedirect.com/science/article/pii/S1347861319303391
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