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Pharmacophore-Based Virtual Screening and In-Silico Explorations of Biomolecules (Curcumin Derivatives) of <i>Curcuma longa</i> as Potential Lead Inhibitors of ERBB and VEGFR-2 for the Treatment of Colorectal Cancer

The newly FDA-approved drug, Axitinib, is an effective therapy against RTKs, but it possesses severe adverse effects like hypertension, stomatitis, and dose-dependent toxicity. In order to ameliorate Axitinib’s downsides, the current study is expedited to search for energetically stable and optimize...

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Váldodahkkit: Syeda Abida Ejaz, Mubashir Aziz, Mohamed Fawzy Ramadan, Ammara Fayyaz, Muhammad Sajjad Bilal
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2023-05-01
Ráidu:Molecules
Fáttát:
Liŋkkat:https://www.mdpi.com/1420-3049/28/10/4044
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