Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

ABSTRACT Glycoconjugate vaccines are a critical component of the medical arsenal against infectious diseases. This established field continues, however, to experience failures in the clinic. The lack of fundamental understanding of factors controlling clinical efficacy of glycoconjugate vaccines is...

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Autori principali:	Fikri Avci, Francesco Berti, Peter Dull, John Hennessey, Viliam Pavliak, A. Krishna Prasad, Willie Vann, Michael Wacker, Olivier Marcq
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2019-10-01
Serie:	mSphere
Soggetti:	T-cell immunity capsular polysaccharide carrier protein clinical trials glycoconjugates immunity
Accesso online:	https://journals.asm.org/doi/10.1128/mSphere.00520-19
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