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Herpes Simplex Virus Type 2 Infection-Induced Expression of CXCR3 Ligands Promotes CD4+ T Cell Migration and Is Regulated by the Viral Immediate-Early Protein ICP4

HSV-2 infection-induced CXCR3 ligands are important for the recruitment of virus-specific CD8+ T cells, but their impact on CD4+ T cell trafficking remains to be further determined. Given that recruitment of CD4+ T cells to infection areas may be one of the mechanisms that account for HSV-2 infectio...

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Principais autores: Mudan Zhang, Xu Deng, Xinmeng Guan, Lanlan Geng, Ming Fu, Binman Zhang, Rui Chen, Huimin Hu, Kai Hu, Di Zhang, Mei Li, Yalan Liu, Sitang Gong, Qinxue Hu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-12-01
coleção:Frontiers in Immunology
Assuntos:
HSV-2
CXCR3 ligands
CD4+ T cells
recruitment
ICP4
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02932/full
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