An Integrated Workflow for Proteome-Wide Off-Target Identification and Polypharmacology Drug Design
Polypharmacology, which focuses on designing drugs to target multiple receptors, has emerged as a new paradigm in drug discovery. To rationally design multi-target drugs, it is fundamental to understand protein-ligand interactions on a proteome scale. We have developed a Proteome-wide Off-target Pip...
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| Główni autorzy: | , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Tsinghua University Press
2014-06-01
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| Seria: | Tsinghua Science and Technology |
| Hasła przedmiotowe: | |
| Dostęp online: | https://www.sciopen.com/article/10.1109/TST.2014.6838198 |
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