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The Role of Nitric Oxide in HSV-1 Infection: The Use of an Inducible Nitric Synthase Inhibitor Aminoguanidine to Treat Neuroinflammation

Herpes simplex virus-1 (HSV-1) is a neurotropic virus that can infect the brain, and an uncontrolled infection can lead to severe encephalitis. NO can exert both antiviral as well as cytotoxic effects in the central nervous system (CNS) depending on its concentration and site of infection. In this s...

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Principais autores: Magdalena Patrycy, Martyna Janicka, Agnieszka Kauc, Aleksandra Osińska, Małgorzata Antos-Bielska, Klaudia Bylińska, Oliwia Obuch-Woszczatyńska, Paweł Szymański, Marcin Chodkowski, Małgorzata Krzyżowska
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-09-01
Serier:Microorganisms
Fag:
nitric oxide
HSV-1
aminoguanidine
neuroinflammation
beta amyloid
Online adgang:https://www.mdpi.com/2076-2607/13/10/2222
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