Fasudil Loaded PLGA Microspheres as Potential Intravitreal Depot Formulation for Glaucoma Therapy

Rho-associated protein kinase (ROCK) inhibitors allow for causative glaucoma therapy. Unfortunately, topically applied ROCK inhibitors suffer from high incidence of hyperemia and low intraocular bioavailability. Therefore, we propose the use of poly (lactide-co-glycolide) (PLGA) microspheres as a de...

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Detalhes bibliográficos

Principais autores:	Raphael Mietzner, Christian Kade, Franziska Froemel, Diana Pauly, W. Daniel Stamer, Andreas Ohlmann, Joachim Wegener, Rudolf Fuchshofer, Miriam Breunig
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-07-01
Colecção:	Pharmaceutics
Assuntos:	drug delivery glaucoma ROCK inhibitor fasudil PLGA microspheres intravitreal injection
Acesso em linha:	https://www.mdpi.com/1999-4923/12/8/706
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