Brain-targeting drug delivery systems: The state of the art in treatment of glioblastoma

Glioblastoma (GBM) is the most prevalent primary malignant brain tumor, characterized by a high mortality rate and a poor prognosis. The blood-brain barrier (BBB) and the blood-tumor barrier (BTB) present significant obstacles to the efficacy of tumor-targeted pharmacotherapy, thereby impeding the t...

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Hlavní autoři:	Bo Sun, Rong Li, Ning Ji, Han Liu, Hongxiang Wang, Chao Chen, Long Bai, Jiacan Su, Juxiang Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2025-02-01
Edice:	Materials Today Bio
Témata:	Glioblastoma Blood brain barrier Blood-tumor barrier Brain targeting drug delivery system Nanoparticles
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2590006425000018
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