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Brain-derived neurotrophic factor prevents LPS-induced dysregulation of GABAergic interneuron markers in mouse hippocampus

BackgroundInflammation causes reduced markers of GABAergic interneurons and brain-derived neurotrophic factor (BDNF) in the hippocampus, features often associated with neuropsychiatric disease pathophysiology. However, the mechanism connecting inflammation to GABAergic markers remains unclear. We hy...

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Principais autores: Sara Rezaei, Mounira Banasr, Thomas D. Prevot, Yashika Bansal, Erica Vieira, Etienne Sibille
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-09-01
coleção:Frontiers in Cellular Neuroscience
Assuntos:
brain-derived neurotrophic factor
lipopolysaccharide
GABAergic interneurons
inflammation
neuropsychiatric disorders
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncel.2025.1675003/full
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