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Apolipoprotein E COG 133 mimetic peptide improves 5-fluorouracil-induced intestinal mucositis

<p>Abstract</p> <p>Background</p> <p>Intestinal mucositis is one of the major troublesome side effects of anticancer chemotherapy leading to poor patient compliance. In this study we addressed the role of the novel apolipoprotein E (ApoE) COG 133 mimetic peptide in 5-fluorouracil (5-FU)-challenged S...

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Autori principali: Azevedo Orleâncio Gomes R, Oliveira Renato André C, Oliveira Bruna, Zaja-Milatovic Snjezana, Araújo Celina, Wong Deysi Viviana T, Costa Tiê, Lucena Herene Barros, Lima-Júnior Roberto César P, Ribeiro Ronaldo A, Warren Cirle A, Lima Aldo Ângelo M, Vitek Michael P, Guerrant Richard L, Oriá Reinaldo B
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2012-07-01
Serie:BMC Gastroenterology
Soggetti:
Mucositis
Apolipoprotein E
5-fluorouracil
Inflammation
Cytokines
Accesso online:http://www.biomedcentral.com/1471-230X/12/35
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