Multicellular ovarian cancer spheroids: novel 3D model to mimic tumour complexity

Abstract In vitro, spheroid models have become well established in cancer research because they can better mimic certain characteristics of in vivo tumours. However, interaction with the tumour microenvironment, such as cancer-associated fibroblasts, plays a key role in tumour progression. We initia...

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Hlavní autoři:	Inken Flörkemeier, Lisa K. Antons, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, Sandra Krüger, Regina Scherließ, Astrid Dempfle, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-10-01
Edice:	Scientific Reports
Témata:	Ovarian cancer and fibroblast Spheroids Co-culture model Tumour microenvironment
On-line přístup:	https://doi.org/10.1038/s41598-024-73680-6
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