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New insights on antibacterial mode of action of blue-light photoactivated berberine and curcumin-antibiotic combinations against Staphylococcus aureus

Antimicrobial photodynamic inactivation (aPDI), using photosensitisers in combination with antibiotics, is a promising multi-target strategy to address antibiotic resistance, particularly in wound infections. This study aimed to elucidate the antibacterial mode of action of combinations of berberine...

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Principais autores: Ariana S.C. Gonçalves, José R. Fernandes, Maria José Saavedra, Nuno M. Guimarães, Cristiana Pereira, Manuel Simões, Anabela Borges
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-04-01
coleção:Photodiagnosis and Photodynamic Therapy
Assuntos:
Antibiotic resistance
Antimicrobial photodynamic inactivation
Berberine/Curcumin-antibiotic combinations
Multi-target
Oxidative stress
S. aureus wound infections
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1572100025000444
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