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Targeted gene silencing in mouse testicular Sertoli and Leydig cells using adeno-associated virus vectors

Researchers commonly use cyclization recombination enzyme/locus of X-over P1 (Cre/loxP) technology-based conditional gene knockouts of model mice to investigate the functional roles of genes of interest in Sertoli and Leydig cells within the testis. However, the shortcomings of these genetic tools i...

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Principais autores: Jing Pang, Mao-Xing Xu, Xiao-Yu Wang, Xu Feng, Yi-Man Duan, Xiao-Yan Zheng, Yu-Qian Chen, Wen Yin, Ying Liu, Ju-Xue Li
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2025-09-01
Series:Asian Journal of Andrology
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Acceso en liña:https://journals.lww.com/10.4103/aja2024120
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