Role of the Fyn-PKCδ signaling in SE-induced neuroinflammation and epileptogenesis in experimental models of temporal lobe epilepsy

Status epilepticus (SE) induces neuroinflammation and epileptogenesis, but the mechanisms are not yet fully delineated. The Fyn, a non-receptor Src family tyrosine kinase (SFK), and its immediate downstream target, PKCδ are emerging as potential mediators of neuroinflammation. In order to first dete...

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Autors principals:	Shaunik Sharma, Steven Carlson, Sreekanth Puttachary, Souvarish Sarkar, Lucas Showman, Marson Putra, Anumantha G. Kanthasamy, Thimmasettappa Thippeswamy
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2018-02-01
Col·lecció:	Neurobiology of Disease
Matèries:	Microglia Neuroinflammation Status epilepticus Epileptogenesis Video-EEG Neurodegeneration
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S096999611730270X
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