The RANK–RANKL–OPG System: A Multifaceted Regulator of Homeostasis, Immunity, and Cancer

The RANK–RANKL–OPG system is a complex signaling pathway that plays a critical role in bone metabolism, mammary epithelial cell development, immune function, and cancer. RANKL is a ligand that binds to RANK, a receptor expressed on osteoclasts, dendritic cells, T cells, and other cells. RANKL signal...

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Bibliografiske detaljer

Principais autores:	Diego De Leon-Oliva, Silvestra Barrena-Blázquez, Laura Jiménez-Álvarez, Oscar Fraile-Martinez, Cielo García-Montero, Laura López-González, Diego Torres-Carranza, Luis M. García-Puente, Sara T. Carranza, Miguel Ángel Álvarez-Mon, Melchor Álvarez-Mon, Raul Diaz, Miguel A. Ortega
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2023-09-01
Serier:	Medicina
Fag:	RANKL RANK osteoclast immune system bone metastasis breast cancer
Online adgang:	https://www.mdpi.com/1648-9144/59/10/1752
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