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Oviductus Ranae alleviates D-galactose-induced ovarian aging by inhibiting ferroptosis and regulating the GPX4/ACSL4 pathway

Abstract Background Ovarian dysfunction caused by aging restricts female reproductive capacity and causes age-related health problems. Ferroptosis is an important mode of cell death during accelerated aging. Oviductus Ranae (OR), a traditional Chinese medicine, has been used to treat ovarian age-rel...

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Huvudupphov: Xiaomei Ling, Cong Xie, Ming Li, Jie Li, Shun Liu, Liyue Sun, Xinxin Zeng, Zhen Zhang, Xuhui Zhang, Lei Liang
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2025-11-01
Serie:Journal of Ovarian Research
Ämnen:
Oviductus Ranae
Ovarian aging
Ovarian granulosa cell
Ferroptosis
Lipid peroxidation
Länkar:https://doi.org/10.1186/s13048-025-01857-2
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