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Microglia-mediated synaptic pruning is impaired in sleep-deprived adolescent mice

The detrimental effects of sleep insufficiency have been extensively explored. However, only a few studies have addressed this issue in adolescents. In the present study, we examined and compared the effects of 72 h paradoxical sleep deprivation (SD) on adolescent (5 weeks old) and adult (~12 weeks...

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Autori principali: Li-Heng Tuan, Li-Jen Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019-10-01
Serie:Neurobiology of Disease
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Accesso online:http://www.sciencedirect.com/science/article/pii/S096999611830264X
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