Dissecting the Immunological Microenvironment of Glioma Based on IDH Status: Implications for Immunotherapy

Gliomas, particularly IDH-wildtype ones, are associated with poor prognosis, yet their immunological landscape remains uncertain. We analyzed RNA sequencing data from 55 glioma patients, estimating immune infiltration with CIBERSORTx and immune cell states via Ecotyper. IDH-wildtype gliomas showed s...

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Detalhes bibliográficos

Principais autores:	Miyu Kikuchi, Hirokazu Takami, Yukari Kobayashi, Koji Nagaoka, Yosuke Kitagawa, Masashi Nomura, Shunsaku Takayanagi, Shota Tanaka, Nobuhito Saito, Kazuhiro Kakimi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-07-01
Colecção:	Cells
Assuntos:	glioma IDH status tumor microenvironment immunotherapy tumor-infiltrating lymphocytes immune checkpoint inhibitors
Acesso em linha:	https://www.mdpi.com/2073-4409/14/13/1035
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