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LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma

Summary: Hepatocellular carcinoma (HCC) is highly heterogeneous, and stemness signatures are frequently elevated in HCC tumor cells to generate heterogeneous subtypes via multidirectional differentiation. However, the mechanisms affecting the regulation of stemness in HCC remain unclear. In this stu...

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Bibliografiset tiedot
Päätekijät: Jianping Liao, Jiahong Wang, Yu Xu, Yong Wu, Meifeng Wang, Qiudong Zhao, Xiaodan Tan, Yan Meng, Lixin Wei, Aimin Huang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2023-06-01
Sarja:iScience
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Linkit:http://www.sciencedirect.com/science/article/pii/S2589004223008313
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