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Rickettsia Vaccine Candidate pVAX1-OmpB24 Stimulates TCD4+INF-γ+ and TCD8+INF-γ+ Lymphocytes in Autologous Co-Culture of Human Cells

Background: In recent years, promising vaccination strategies against rickettsiosis have been described in experimental animal models and human cells. OmpB is considered an immunodominant antigen that is recognized by T and B cells. The aim of this study was to identify TCD4+INF-γ+ and TCD8+INF-γ+ l...

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Principais autores: Karla Dzul-Rosado, Luis Donis-Maturano, Juan Arias-León, Jesús Machado-Contreras, Guillermo Valencia-Pacheco, Candi Panti-Balam, Javier Balam-Romero, Angela Ku-González, Gaspar Peniche-Lara, Juan Mosqueda, Oscar E. Zazueta, Cesar Lugo-Caballero, Fernando Puerto-Manzano
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-01-01
Serier:Vaccines
Fag:
activated lymphocytes
pVAX1-OmpB24
<i>Rickettsia rickettsii</i>
Online adgang:https://www.mdpi.com/2076-393X/11/1/173
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