Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation[S]

Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced endothelial stiffening is mediated by CD36-dependen...

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Autors principals:	Myung-Jin Oh, Chongxu Zhang, Elizabeth LeMaster, Crystal Adamos, Evgeny Berdyshev, Yedida Bogachkov, Erin E. Kohler, Jugajyoti Baruah, Yun Fang, Dean E. Schraufnagel, Kishore K. Wary, Irena Levitan
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2016-05-01
Col·lecció:	Journal of Lipid Research
Matèries:	angiogenesis endothelial stiffness RhoA
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0022227520309834
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