Comparative assessment of the effects of dotinurad and febuxostat on the renal function in chronic kidney disease patients with hyperuricemia

Abstract Although hyperuricemia is associated with chronic kidney disease (CKD), the impact of uric acid (UA)-lowering drugs on CKD has been controversial. Previous investigations have primarily included xanthine oxidase inhibitors; therefore, research of dotinurad, a recently developed selective ur...

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主要な著者:	Tomoaki Takata, Sosuke Taniguchi, Yukari Mae, Kana Kageyama, Yudai Fujino, Takuji Iyama, Katsuya Hikita, Takaaki Sugihara, Hajime Isomoto
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-03-01
シリーズ:	Scientific Reports
主題:	Chronic kidney disease Dotinurad Hyperuricemia Selective urate reabsorption inhibitor Urate transporter-1 Urinary uric acid
オンライン･アクセス:	https://doi.org/10.1038/s41598-025-94020-2
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