Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma

Abstract Background The prognostic impact of EGFR mutation as major targetable somatic gene variant on lung adenocarcinoma is controversial. KRAS is another major somatic variant in lung adenocarcinoma, and a therapeutic agent for KRAS G12C became available in clinical settings. These mutations repr...

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Autors principals:	Masaoki Ito, Yoshihiro Miyata, Kei Kushitani, Daisuke Ueda, Yukio Takeshima, Morihito Okada
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-03-01
Col·lecció:	BMC Cancer
Matèries:	EGFR IASLC KRAS Lung adenocarcinoma Prognosis Recurrence
Accés en línia:	https://doi.org/10.1186/s12885-023-10716-6
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