Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases
Abstract The sigma-1 receptor (Sig-1R) is a chaperone that resides mainly at the mitochondrion-associated endoplasmic reticulum (ER) membrane (called the MAMs) and acts as a dynamic pluripotent modulator in living systems. At the MAM, the Sig-1R is known to play a role in regulating the Ca2+ signali...
Gardado en:
| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2017-09-01
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| Series: | Journal of Biomedical Science |
| Assuntos: | |
| Acceso en liña: | http://link.springer.com/article/10.1186/s12929-017-0380-6 |
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