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SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting

Caloric restriction (CR) has been shown to prevent the onset of insulin resistance and to delay age-related physiological decline in mammalian organisms. SIRT1, a NAD+-dependent deacetylase enzyme, has been suggested to mediate the adaptive responses to CR, leading to the speculation that SIRT1 acti...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Marie Boutant, Sameer S. Kulkarni, Magali Joffraud, Frédéric Raymond, Sylviane Métairon, Patrick Descombes, Carles Cantó
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2016-03-01
Rangatū:Cell Reports
Ngā marau:
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S221112471630081X
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