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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells

IntroductionIn mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells.MethodsWe used 148 publicly available bulk RNA-seq...

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Principais autores: Steven Timmermans, Charlotte Wallaeys, Somara De Beul, Natalia Garcia-Gonzales, Claude Libert
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-02-01
Serija:Frontiers in Immunology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1543059/full
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