Sophflarines F–K: matrine-based alkaloids with a rare aromatic system from Sophora flavescens and their anti-inflammatory and synergistic antibacterial effects

Abstract Six new matrine-based alkaloids, sophflarines F–K (1–6), featuring a rare aromatic system, were obtained from the water-soluble alkaloid fractions of Sophora flavescens by UV-guided separation. Their structures were elucidated by the interpretation of spectroscopic analyses, quantum chemica...

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Autori principali:	Ding Luo, Le-Yan Wang, Xiang-Feng Zhao, Xiao-Lin Huang, Yang-Yi Hu, Qiong-Yun Jing, Yan-Jun Chen, He Tian, Si-Yan Chen, Yu-Yan Wang, Xian-Hui Huang, Zhen-Ling Zeng, Xiao-Ping Liao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	SpringerOpen 2026-04-01
Serie:	Natural Products and Bioprospecting
Soggetti:	Matrine type alkaloids Sophora flavescens X-Ray diffraction Anti inflammatory Antibacterial synergy
Accesso online:	https://doi.org/10.1007/s13659-026-00595-2
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