Female sex is linked to a stronger association between sTREM2 and CSF p-tau in Alzheimer’s disease

Abstract In Alzheimer’s disease (AD), Aβ triggers p-tau secretion, which drives tau aggregation. Therefore, it is critical to characterize modulators of Aβ-related p-tau increases which may alter AD trajectories. Here, we assessed whether factors known to alter tau levels in AD modulate the associat...

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Hlavní autoři:	Davina Biel, Marc Suárez-Calvet, Anna Dewenter, Anna Steward, Sebastian N Roemer, Amir Dehsarvi, Zeyu Zhu, Julia Pescoller, Lukas Frontzkowski, Annika Kreuzer, Christian Haass, Michael Schöll, Matthias Brendel, Nicolai Franzmeier
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer Nature 2025-01-01
Edice:	EMBO Molecular Medicine
Témata:	Alzheimer’s Disease Microglia sTREM2 p-tau Sex Differences
On-line přístup:	https://doi.org/10.1038/s44321-024-00190-3
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