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Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver.

We recently identified a nuclear-encoded miRNA (miR-181c) in cardiomyocytes that can translocate into mitochondria to regulate mitochondrial gene mt-COX1 and influence obesity-induced cardiac dysfunction through the mitochondrial pathway. Because liver plays a pivotal role during obesity, we hypothe...

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Principais autores: Kei Akiyoshi, Gretha J Boersma, Miranda D Johnson, Fernanda Carrizo Velasquez, Brittany Dunkerly-Eyring, Shannon O'Brien, Atsushi Yamaguchi, Charles Steenbergen, Kellie L K Tamashiro, Samarjit Das
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2021-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0256973&type=printable
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