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Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin

Abstract Background Human plasma gelsolin (pGSN) is a multifunctional actin-binding protein involved in a variety of biological processes, including neutralization of pro-inflammatory molecules such as lipopolysaccharide (LPS) and lipoteichoic acid (LTA) and modulation of host inflammatory response....

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Main Authors: Ewelina Piktel, Urszula Wnorowska, Mateusz Cieśluk, Piotr Deptula, Katarzyna Pogoda, Iwona Misztalewska-Turkowicz, Paulina Paprocka, Katarzyna Niemirowicz-Laskowska, Agnieszka Z. Wilczewska, Paul A. Janmey, Robert Bucki
Format: Artigo
Language:Inglês
Published: BMC 2019-02-01
Series:Journal of Nanobiotechnology
Subjects:
Gelsolin
Inflammation
Skin diseases
PBP10
Magnetic nanoparticles
Online Access:http://link.springer.com/article/10.1186/s12951-019-0455-5
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