Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15

Abstract DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflammatory responses. However, whether and how IFN signaling in turn impacts the DNA replication process has remained elusive. Here we show that basal levels of the IFN-stimulated gene 15, ISG15,...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ramona N. Moro, Uddipta Biswas, Suhas S. Kharat, Filip D. Duzanic, Prosun Das, Maria Stavrou, Maria C. Raso, Raimundo Freire, Arnab Ray Chaudhuri, Shyam K. Sharan, Lorenza Penengo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2023-10-01
Colecção:	Nature Communications
Acesso em linha:	https://doi.org/10.1038/s41467-023-41801-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!