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Associations of plasma MMP-9 and MPO with functional outcome in moderate to severe acute ischemic stroke

Abstract Inflammation plays a pivotal role in acute ischemic stroke (AIS), with neutrophil granulocytes acting as major contributors to the post-stroke immune response. Upon degranulation, neutrophils release matrix metalloproteinase-9 (MMP-9) and myeloperoxidase (MPO), both of which may influence f...

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Autors principals: Vivian Vogt, Christoph Vollmuth, Guido Stoll, Felipe A. Montellano, Peter U. Heuschmann, Alexander M. Kollikowski, Mirko Pham, Karl Georg Haeusler, Hermann Neugebauer, Michael K. Schuhmann
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2026-07-01
Col·lecció:Scientific Reports
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Accés en línia:https://doi.org/10.1038/s41598-026-61410-z
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